Basic Information
| Drug ID | DDPD01340 |
|
| Drug Name | Cilazapril | |
| Molecular Weight | 417.4986 | |
| Molecular Formula | C22H31N3O5 | |
| CAS Number | 88768-40-5 | |
| SMILES | CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]1CCCN2CCC[C@H](N2C1=O)C(O)=O | |
| External Links | ||
| DRUGBANK | DB01340 | |
| PubChem Compound | 56330 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.8 | - | 0.8 | - | DRUGBANK |
| Melting Point | 98.0 | ℃ | 98 | ℃ | DRUGBANK |
| Water Solubility | 5000.0 | mg/L | 0.5 | g/100ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.0 | h | 2 | h | Active metabolite; | DRUGBANK |
| Clearance | 14.9 | L/h | 12.3-17.4 | L/h | Total clearance; | DRUGBANK | Clearance | 10.8 | L/h | 10.8 | L/h | Renal clearance; | DRUGBANK |
| Half-life | 1.9 | h | 1.9 | h | distribution half-life; intravenous injection, IV; | DRUGBANK | Half-life | 46.2 | h | 46.2 | h | elimination half-life; intravenous injection, IV; | DRUGBANK |
| Eliminate Route | 91.0 | % | 91 | % | Urinary excretion; intravenous injection, IV; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1