Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01339 ...
Drug Name Vecuronium
Molecular Weight 557.8274
Molecular Formula C34H57N2O4
CAS Number 86029-43-8
SMILES [H][C@@]12C[C@@H]([C@H](OC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](OC(C)=O)[C@H](C[C@]12C)N1CCCCC1)[N+]1(C)CCCCC1
External Links
DRUGBANK DB01339
PubChem Compound 39765
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 228.0 ℃ 228 ℃ PhysProp

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
C Max 130.0 ng/ml 130±20 ng/ml The Pharmacological Basis of Therapeutics
Metabolic 100.0 % 100 % DRUGBANK
Clearance 0.28 L/h/kg 3.0-6.4 ml/min/kg Average clearance; hepatopathy，LD ↓ ; The Pharmacological Basis of Therapeutics
Volume of Distribution 0.35 L/kg 0.19-0.51 L/kg Average volume of distribution; The Pharmacological Basis of Therapeutics
Half-life 1.1 h 51-80 min DRUGBANK
Half-life 1.7 h 0.6-2.8 h different study; chronic liver disease ↑ ; The Pharmacological Basis of Therapeutics
Eliminate Route 57.5 % 40-75 % Faeces excretion; DRUGBANK
Eliminate Route 30.0 % 30 % Urinary excretion; DRUGBANK
Eliminate Route 30.0 % <30 % Urinary excretion; Unchanged drug; DRUGBANK
Eliminate Route 20.0 % 20 % Urinary excretion; Unchanged drug; The Pharmacological Basis of Therapeutics
Protein Binding 69.0 % 69 % The Pharmacological Basis of Therapeutics

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1