Basic Information

Drug ID DDPD01332 ...
Drug Name Ceftizoxime
Molecular Weight 383.403
Molecular Formula C13H13N5O5S2
CAS Number 68401-81-0
SMILES [H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CSC(N)=N1)C(O)=O
External Links
DRUGBANK DB01332
PubChem Compound 6533629
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 277.0 277 Takaya, T., Masugi, T., Takasugi, H. and Kochi, H.;U.S. Patent 4,166,115; assigned to Fuji- sawa Pharmaceutical & ., Ltd.

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Metabolic 0 % 0 % DRUGBANK
Metabolic 0 % ~0 % Urinary excretion; DRUGBANK
Clearance 0.13 L/h/kg 2.1 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 21.5 L 15-28 L Apparent volume of distribution; DRUGBANK
Volume of Distribution 0.20 L/kg 0.2 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.5 h 1.5 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 30.0 % 30 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1