Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01329 ...
Drug Name Cefoperazone
Molecular Weight 645.67
Molecular Formula C25H27N9O8S2
CAS Number 62893-19-0
SMILES [H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@@]2([H])NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O
External Links
DRUGBANK DB01329
PubChem Compound 44185

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -0.74 - -0.74 - HANSCH,C ET AL. (1995)
Melting Point 189.0 ℃ 188-190 ℃ Saikawa, I., Takano, S., Yoshida, C., Takashima, 0..Momonoi, K., Kuroda, S., Komatsu, M., Yasuda, T.and Kodama, Y.; British Patent 1,508,071; April 19,1978; assigned to Toyama Chemical Co., Ltd. and U.S. Patent 4,110,327; August 29,1978; also assigned to Toyama Chemical Co., Ltd.

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.0780 L/h/kg 1.3 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.17 L/kg 0.17 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 2.0 h 2 h elimination half-life; DRUGBANK
Half-life 1.8 h 1.8 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1