Basic Information
| Drug ID | DDPD01319 |
|
| Drug Name | Fosamprenavir | |
| Molecular Weight | 585.607 | |
| Molecular Formula | C25H36N3O9PS | |
| CAS Number | 226700-79-4 | |
| SMILES | CC(C)CN(C[C@@H](OP(O)(O)=O)[C@H](CC1=CC=CC=C1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)C1=CC=C(N)C=C1 | |
| External Links | ||
| DRUGBANK | DB01319 | |
| PubChem Compound | 131536 | |
| PDR | 603 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 7.7 | h | ~7.7 | h | elimination half-life; Active metabolite; | DRUGBANK |
| Protein Binding | 90.0 | % | ~90 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 46.0 | mg/kg/day | 46 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for infants | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for infants | 90.0 | mg/kg/day | 90 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 36.0 | mg/kg/day | 36 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 1400.0 | mg/day | 1400 | mg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 1400.0 | mg/day | 1400 | mg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 46.0 | mg/kg/day | 46 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 90.0 | mg/kg/day | 90 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 46.0 | mg/kg/day | 46 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for children | 90.0 | mg/kg/day | 90 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for adolescents | 36.0 | mg/kg/day | 36 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for adolescents | 1400.0 | mg/day | 1400 | mg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for adolescents | 60.0 | mg/kg/day | 60 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for adolescents | 2800.0 | mg/kg/day | 2800 | mg/kg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for adults | 2800.0 | mg/day | 2800 | mg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
| Max dose for geriatric | 2800.0 | mg/day | 2800 | mg/day | PO, oral | Lexiva | fosamprenavir calcium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1