Basic Information

Drug ID DDPD01303 ...
Drug Name Oxtriphylline
Molecular Weight 283.3268
Molecular Formula C12H21N5O3
CAS Number 4499-40-5
SMILES C[N+](C)(C)CCO.CN1C2=C([N-]C=N2)C(=O)N(C)C1=O
External Links
DRUGBANK DB01303
PubChem Compound 656652
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.0870 L/h/kg 1.45 ml/kg/min Average clearance; Children; DRUGBANK
Clearance 0.000650 L/h/kg 0.65 ml/kg/h Average clearance; normal,healthy; adults; DRUGBANK
Volume of Distribution 0.50 L/kg 0.3–0.7 L/kg Apparent volume of distribution; Children; adults; DRUGBANK
Half-life 7.9 h 3-12.8 h elimination half-life; normal,healthy; DRUGBANK
Half-life 5.5 h 1.5-9.5 h elimination half-life; Children; DRUGBANK
Half-life 36.5 h 15-58 h elimination half-life; Prem, premature; DRUGBANK
Protein Binding 56.0 % ~56 % plasma proteins; adults; Children; human, homo sapiens; DRUGBANK
Protein Binding 36.0 % ~36 % plasma proteins; Prem, premature; human, homo sapiens; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1