Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01297 ...
Drug Name Practolol
Molecular Weight 266.3361
Molecular Formula C14H22N2O3
CAS Number 6673-35-4
SMILES CC(C)NCC(O)COC1=CC=C(NC(C)=O)C=C1
External Links
DRUGBANK DB01297
PubChem Compound 4883

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Caco-2 Permeability -6.05 - -6.05 - ADME Research, USCD
Log P 0.79 - 0.79 - HANSCH,C ET AL. (1995)
Melting Point 135.0 ℃ 134-136 ℃ PhysProp

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.14 L/h/kg 2.28 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 12.2 h 12.2 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1