Basic Information

Drug ID DDPD01283 ...
Drug Name Lumiracoxib
Molecular Weight 293.721
Molecular Formula C15H13ClFNO2
CAS Number 220991-20-8
SMILES CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(CC(O)=O)=C1
External Links
DRUGBANK DB01283
PubChem Compound 151166

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 3.9 - 3.9 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 74.0 % 74 % PO, oral; DRUGBANK
Half-life 4.0 h ~4 h terminal half-life; DRUGBANK
Toxicity Lethal Dose 600.0 mg/kg 600.0 mg/kg Oral single dose; mouse; DRUGBANK
Toxicity Lethal Dose 500.0 mg/kg 500.0 mg/kg Oral single dose; Rattus, Rat; DRUGBANK
Toxicity Lethal Dose 752.0 mg/kg 752.0 mg/kg mouse; DRUGBANK
Toxicity Lethal Dose 1000.0 mg/kg 1000.0 mg/kg Rattus, Rat; DRUGBANK
Protein Binding 98.0 % ≥98 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1