Basic Information
| Drug ID | DDPD01274 |
|
| Drug Name | Arformoterol | |
| Molecular Weight | 344.4049 | |
| Molecular Formula | C19H24N2O4 | |
| CAS Number | 67346-49-0 | |
| SMILES | COC1=CC=C(C[C@@H](C)NC[C@H](O)C2=CC(NC=O)=C(O)C=C2)C=C1 | |
| External Links | ||
| DRUGBANK | DB01274 | |
| PubChem Compound | 3083544 | |
| PDR | 552 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.2 | - | 2.2 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 100.0 | % | ~100 | % | DRUGBANK | |
| Clearance | 8.9 | L/h | 8.9 | L/h | Renal clearance; normal,healthy; Male, men; | DRUGBANK |
| Half-life | 26.0 | h | 26 | h | COPD, Chronic obstructive pulmonary disease; | DRUGBANK |
| Eliminate Route | 63.0 | % | 63 | % | Urinary excretion; PO, oral; Male, men; normal,healthy; human, homo sapiens; | DRUGBANK | Eliminate Route | 11.0 | % | 11 | % | Faeces excretion; PO, oral; Male, men; normal,healthy; human, homo sapiens; | DRUGBANK |
| Protein Binding | 58.5 | % | 52-65 | % | plasma proteins; high protein binding; human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 0.03 | mg/day | 30 | mcg/day | inhalation, IH | Brovana | arformoterol tartrate | PDR |
| Max dose for elderly | 0.03 | mg/day | 30 | mcg/day | inhalation, IH | Brovana | arformoterol tartrate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1