Basic Information
| Drug ID | DDPD01273 |
|
| Drug Name | Varenicline | |
| Molecular Weight | 211.268 | |
| Molecular Formula | C13H13N3 | |
| CAS Number | 249296-44-4 | |
| SMILES | C1C2CNCC1C1=C2C=C2N=CC=NC2=C1 | |
| External Links | ||
| DRUGBANK | DB01273 | |
| T3DB | T3D2577 | |
| PubChem Compound | 5310966 | |
| PDR | 466 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.9 | - | 0.9 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 10.0 | % | <10 | % | DRUGBANK | Metabolic | 81.0 | % | 81 | % | Urinary excretion; | DRUGBANK |
| Half-life | 24.0 | h | ~24 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 92.0 | % | 92 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 20.0 | % | <20 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Frequency | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 1.0 | mg | 1 | mg | PO, oral | bid | Chantix | varenicline | PDR |
| Max dose for elderly | 1.0 | mg | 1 | mg | PO, oral | bid | Chantix | varenicline | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1