| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
| Bioavailability |
87.0 |
% |
87 |
% |
PO, oral; food; |
food → ; |
DRUGBANK |
| T Max |
2.0 |
h |
2 |
h |
PO, oral; food; |
food → ; |
DRUGBANK |
| Metabolic |
79.0 |
% |
79 |
% |
|
|
DRUGBANK |
| Clearance |
21.0 |
L/h |
350.0 |
ml/min |
|
|
DRUGBANK |
Clearance |
0.36 |
L/h/kg |
6 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
198.0 |
L |
198.0 |
L |
|
|
DRUGBANK |
Volume of Distribution |
2.8 |
L/kg |
2.8 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
12.4 |
h |
~12.4 |
h |
|
|
DRUGBANK |
Half-life |
11.0 |
h |
~11 |
h |
different study; |
|
DRUGBANK |
Half-life |
12.0 |
h |
12 |
h |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
87.0 |
% |
87 |
% |
Urinary excretion; |
|
DRUGBANK |
Eliminate Route |
13.0 |
% |
13 |
% |
Faeces excretion; |
|
DRUGBANK |
Eliminate Route |
79.0 |
% |
~79 |
% |
Urinary excretion; Unchanged drug; |
|
DRUGBANK |
| Protein Binding |
38.0 |
% |
38 |
% |
|
|
DRUGBANK |
