Basic Information
| Drug ID | DDPD01247 |
|
| Drug Name | Isocarboxazid | |
| Molecular Weight | 231.2505 | |
| Molecular Formula | C12H13N3O2 | |
| CAS Number | 59-63-2 | |
| SMILES | CC1=CC(=NO1)C(=O)NNCC1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB01247 | |
| T3DB | T3D3033 | |
| PubChem Compound | 3759 | |
| PDR | 1355 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.49 | - | 1.49 | - | 'MSDS' |
| Boiling Point | 394.5 | ℃ | 394.5 | ℃ | 'MSDS' |
| Melting Point | 105.5 | ℃ | 105-106 | ℃ | 'MSDS' |
| pKa | 10.4 | - | 10.4 | - | SANGSTER (1994) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.5 | h | 1-2 | h | PO, oral; | DRUGBANK |
| Half-life | 2.8 | h | 1.5-4 | h | DRUGBANK | |
| Eliminate Route | 42.5 | % | 42.5 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 22.0 | % | 22 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 60.0 | mg/day | 60 | mg/day | PO, oral | Marplan | isocarboxazid | PDR |
| Max dose for adults | 60.0 | mg/day | 60 | mg/day | PO, oral | Marplan | isocarboxazid | PDR |
| Max dose for elderly | 60.0 | mg/day | 60 | mg/day | PO, oral | Marplan | isocarboxazid | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1