Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01239 ...
Drug Name Chlorprothixene
Molecular Weight 315.86
Molecular Formula C18H18ClNS
CAS Number 113-59-7
SMILES CN(C)CC\C=C1\C2=CC=CC=C2SC2=CC=C(Cl)C=C12
External Links
DRUGBANK DB01239
T3DB T3D3031
PubChem Compound 667466

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 5.18 - 5.18 - HANSCH,C ET AL. (1995)
Melting Point 153.5 ℃ 153-154 ℃ Sprague, J.M. and Engelhardt, E.L.; US. Patent 2,951,082; August 30, 1960; assigned to Merck & Co., Inc. Schlapfer, R. and Spiegelberg, H.; US. Patent 3,115,502; December 24,1963; assigned to Hoffmann-LaRoche Inc.
Water Solubility 0.295 mg/L 0.295 mg/L DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.69 L/h/kg 11.5 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 13.7 L/kg 13.7 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 10.0 h 8-12 h DRUGBANK
Half-life 25.8 h 25.8 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1