Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01225 ...
Drug Name Enoxaparin
Molecular Weight Not Available
CAS Number Not Available
SMILES Not Available
External Links
DRUGBANK DB01225
PubChem Compound 419492895
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -13.2 - -13.2 - DRUGBANK
Water Solubility 200000.0 mg/L >200 mg/mL DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
Bioavailability 100.0 % ~100 % subcutaneous injection, SC; DRUGBANK
Bioavailability 92.0 % 92.0 % subcutaneous injection, SC; The Pharmacological Basis of Therapeutics
C Max 145.0 ng/ml 145±45 ng/ml subcutaneous injection, SC; Active metabolite; adults; normal,healthy; The Pharmacological Basis of Therapeutics
C Max 414.0 ng/ml 414±87 ng/ml subcutaneous injection, SC; Active metabolite; adults; normal,healthy; The Pharmacological Basis of Therapeutics
T Max 3.0 h 3.0 h subcutaneous injection, SC; adults; normal,healthy; The Pharmacological Basis of Therapeutics
Clearance 0.0180 L/h/kg 0.3±0.1 ml/min/kg RD, renal impairment, Renal disease，including uremia ↓ ; The Pharmacological Basis of Therapeutics
Volume of Distribution 4.3 L 4.3 L DRUGBANK
Volume of Distribution 0.12 L/kg 0.12±0.04 L/kg RD, renal impairment, Renal disease，including uremia → ; The Pharmacological Basis of Therapeutics
Half-life 4.5 h 4.5 h DRUGBANK
Half-life 3.8 h 3.8±1.3 h RD, renal impairment, Renal disease，including uremia ↑ ; The Pharmacological Basis of Therapeutics
Toxicity LD50 5000.0 mg/kg >5000 mg/kg mouse; DRUGBANK
Protein Binding 80.0 % 80 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1