Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Bioavailability |
93.0 |
% |
93 |
% |
|
DRUGBANK |
C Max |
750.0 |
ng/ml |
0.75 |
mcg/ml |
|
DRUGBANK |
Clearance |
1.4 |
L/h/kg |
95.0 |
L/h/70kg |
|
DRUGBANK |
Clearance |
1.1 |
L/h/kg |
19 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
0.37 |
L/kg |
371.3 |
ml/kg |
Total volume of distribution; |
DRUGBANK |
Volume of Distribution |
4.1 |
L/kg |
4060.3 |
ml/kg |
at steady state; |
DRUGBANK |
Volume of Distribution |
2.9 |
L/kg |
2.9 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
3.1 |
h |
186 |
min |
|
DRUGBANK |
Half-life |
2.8 |
h |
2.8 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Eliminate Route |
91.0 |
% |
91 |
% |
Urinary excretion; intravenous injection, IV; |
DRUGBANK |
Eliminate Route |
3.0 |
% |
3 |
% |
Faeces excretion; intravenous injection, IV; |
DRUGBANK |
Protein Binding |
53.5 |
% |
53.5 |
% |
plasma proteins; |
DRUGBANK |