Basic Information
| Drug ID | DDPD01210 |
|
| Drug Name | Levobunolol | |
| Molecular Weight | 291.3853 | |
| Molecular Formula | C17H25NO3 | |
| CAS Number | 47141-42-4 | |
| SMILES | CC(C)(C)NC[C@H](O)COC1=CC=CC2=C1CCCC2=O | |
| External Links | ||
| DRUGBANK | DB01210 | |
| PubChem Compound | 39468 | |
| PDR | 1117 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.4 | - | 2.4 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 210.0 | ℃ | 209-211 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 80.0 | % | 80 | % | DRUGBANK | |
| Half-life | 20.0 | h | 20 | h | DRUGBANK | |
| Toxicity LD50 | 700.0 | mg/kg | 700.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 4.0 | drop/day | 4 | drop/day | ophthalmic administration | Betagan | levobunolol hydrochloride | PDR |
| Max dose for adults | 2.0 | drop/day | 2 | drop/day | ophthalmic administration | Betagan | levobunolol hydrochloride | PDR |
| Max dose for elderly | 4.0 | drop/day | 4 | drop/day | ophthalmic administration | Betagan | levobunolol hydrochloride | PDR |
| Max dose for elderly | 2.0 | drop/day | 2 | drop/day | ophthalmic administration | Betagan | levobunolol hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1