| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
| Bioavailability |
92.0 |
% |
92 |
% |
PO, oral; |
|
DRUGBANK |
Bioavailability |
46.0 |
% |
46 |
% |
PO, oral; antacids; |
antacids ↓ ; |
DRUGBANK |
| Clearance |
0.16 |
L/h/kg |
2.7 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
3.9 |
L/kg |
3.9 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
20.0 |
h |
20(16-30) |
h |
elimination half-life; |
RD, renal impairment, Renal disease，including uremia ↑ ; |
DRUGBANK |
Half-life |
20.0 |
h |
20 |
h |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Protein Binding |
45.0 |
% |
~45 |
% |
plasma proteins; |
|
DRUGBANK |
