Basic Information
| Drug ID | DDPD01194 |
|
| Drug Name | Brinzolamide | |
| Molecular Weight | 383.507 | |
| Molecular Formula | C12H21N3O5S3 | |
| CAS Number | 138890-62-7 | |
| SMILES | CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O | |
| External Links | ||
| DRUGBANK | DB01194 | |
| PubChem Compound | 68844 | |
| PDR | 40 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -1.8 | - | -1.8 | - | DRUGBANK |
| Melting Point | 131.0 | ℃ | 131 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 2664.0 | h | 111 | day | DRUGBANK | |
| Protein Binding | 60.0 | % | ~60 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Azopt | brinzolamide | PDR |
| Max dose for elderly | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Azopt | brinzolamide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1