Basic Information
| Drug ID | DDPD01192 |
|
| Drug Name | Oxymorphone | |
| Molecular Weight | 301.3371 | |
| Molecular Formula | C17H19NO4 | |
| CAS Number | 76-41-5 | |
| SMILES | [H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1(O)CCC2=O | |
| External Links | ||
| DRUGBANK | DB01192 | |
| T3DB | T3D3015 | |
| PubChem Compound | 5284604 | |
| PDR | 23991 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.83 | - | 0.83 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 248.5 | ℃ | 248-249 | ℃ | PhysProp |
| Water Solubility | 24000.0 | mg/L | 24000 | mg/L | DRUGBANK |
| pKa | 8.17 | - | 8.17 | - | SANGSTER (1994) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 49.0 | % | 49 | % | Urinary excretion; | DRUGBANK | Metabolic | 1.9 | % | 1.9 | % | Faeces excretion; | DRUGBANK | Metabolic | 44.1 | % | 44.1 | % | Bile excretion; | DRUGBANK | Metabolic | 0.30 | % | 0.3 | % | lung excretion; | DRUGBANK | Metabolic | 2.6 | % | 2.6 | % | Urinary excretion; | DRUGBANK | Metabolic | 0.10 | % | 0.1 | % | lung excretion; | DRUGBANK |
| Half-life | 1.3 | h | 1.3±0.7 | h | DRUGBANK | |
| Toxicity LD50 | 172.0 | mg/kg | 172.0 | mg/kg | intravenous injection, IV; mouse; | DRUGBANK | Toxicity LD50 | 172.0 | mg/kg | 172.0 | mg/kg | intravenous injection, IV; mouse; | T3DB |
| Eliminate Route | 1.0 | % | <1 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1