Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01191 ...
Drug Name Dexfenfluramine
Molecular Weight 231.2573
Molecular Formula C12H16F3N
CAS Number 3239-44-9
SMILES CCN[C@@H](C)CC1=CC=CC(=C1)C(F)(F)F
External Links
DRUGBANK DB01191
T3DB T3D3014
PubChem Compound 66265

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 3.5 - 3.5 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.66 L/h/kg 11 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 11.0 L/kg 11 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 18.5 h 17-20 h DRUGBANK
Half-life 14.0 h 14 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 36.0 % 36 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1