Basic Information
| Drug ID | DDPD01188 |
|
| Drug Name | Ciclopirox | |
| Molecular Weight | 207.2689 | |
| Molecular Formula | C12H17NO2 | |
| CAS Number | 29342-05-0 | |
| SMILES | CC1=CC(=O)N(O)C(=C1)C1CCCCC1 | |
| External Links | ||
| DRUGBANK | DB01188 | |
| T3DB | T3D3012 | |
| PubChem Compound | 2749 | |
| PDR | 1038 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.3 | - | 2.3 | - | DRUGBANK |
| Melting Point | 143.0 | ℃ | 143 | ℃ | Lohaus, G.and Dittmar, W.; U.S. Patents 3,972,888; August 3, 1976; and 3,883,545; May 13, 1975; both assigned to Hoechst A .G. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 1.7 | h | 1.7 | h | skin/dermal; | DRUGBANK |
| Toxicity LD50 | 10.0 | ml/kg | >10 | ml/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 10.0 | ml/kg | >10 | ml/kg | PO, oral; Rattus, Rat; | T3DB |
| Eliminate Route | 96.0 | % | ~96 | % | Urinary excretion; PO, oral; normal,healthy; human, homo sapiens; | DRUGBANK |
| Protein Binding | 95.5 | % | 94-97 | % | skin/dermal; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1