Basic Information
| Drug ID | DDPD01179 |
|
| Drug Name | Podofilox | |
| Molecular Weight | 414.4053 | |
| Molecular Formula | C22H22O8 | |
| CAS Number | 518-28-5 | |
| SMILES | [H][C@]12COC(=O)[C@]1([H])[C@H](C1=CC(OC)=C(OC)C(OC)=C1)C1=CC3=C(OCO3)C=C1[C@@H]2O | |
| External Links | ||
| DRUGBANK | DB01179 | |
| T3DB | T3D4617 | |
| PubChem Compound | 10607 | |
| PDR | 1207 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.5 | - | 1.5 | - | DRUGBANK |
| Melting Point | 228.0 | ℃ | 228 | ℃ | PhysProp |
| Water Solubility | 100.0 | mg/L | 100 | mg/L | MERCK INDEX 1996) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 9.0 | ng/ml | 1-17 | ng/ml | skin/dermal; | DRUGBANK |
| T Max | 1.5 | h | 1-2 | h | skin/dermal; | DRUGBANK |
| Half-life | 2.8 | h | 1.0-4.5 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 500.0 | mg/day | 0.5 | g/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for children | 0.5 | ml/day | 0.5 | ml/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for adolescents | 500.0 | mg/day | 0.5 | g/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for adolescents | 0.5 | ml/day | 0.5 | ml/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for adults | 500.0 | mg/day | 0.5 | g/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for adults | 0.5 | ml/day | 0.5 | ml/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for elderly | 500.0 | mg/day | 0.5 | g/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
| Max dose for elderly | 0.5 | ml/day | 0.5 | ml/day | skin/dermal | Condylox Topical Solution | podofilox | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1