Basic Information
| Drug ID | DDPD01176 |
|
| Drug Name | Cyclizine | |
| Molecular Weight | 266.3807 | |
| Molecular Formula | C18H22N2 | |
| CAS Number | 82-92-8 | |
| SMILES | CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB01176 | |
| PubChem Compound | 6726 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.0 | - | 3.0 | - | DRUGBANK |
| Melting Point | 106.5 | ℃ | 105.5-107.5 | ℃ | Baltzly, R. and Castillo, J.C.; U.S. Patent 2,630,435; March 3,1953; assigned to Burroughs Wellcome & Co. (U.S.A.) Inc. |
| Water Solubility | 1000.0 | mg/L | 1000 | mg/L | MERCK INDEX 1996); less than |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.87 | L/h/kg | 14.5 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 16.5 | L/kg | 16.5 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 20.0 | h | 20 | h | DRUGBANK | Half-life | 13.5 | h | 13.53 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1