Basic Information
| Drug ID | DDPD01170 |
|
| Drug Name | Guanethidine | |
| Molecular Weight | 198.3085 | |
| Molecular Formula | C10H22N4 | |
| CAS Number | 55-65-2 | |
| SMILES | NC(N)=NCCN1CCCCCCC1 | |
| External Links | ||
| DRUGBANK | DB01170 | |
| PubChem Compound | 3518 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.8 | - | 0.8 | - | DRUGBANK |
| Melting Point | 278.5 | ℃ | 276-281 | ℃ | U.S. Patent 2,928,829 U.S. Patent 3,006,913 U.S. Patent 3,055,882 |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 16.5 | % | 3-30 | % | PO, oral; | DRUGBANK |
| Clearance | 3.4 | L/h | 56.0 | ml/min | Renal clearance; | DRUGBANK |
| Half-life | 36.0 | h | 1.5 | day | DRUGBANK | |
| Toxicity LD50 | 1000.0 | mg/kg | 1000.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1