Basic Information
| Drug ID | DDPD01168 |
|
| Drug Name | Procarbazine | |
| Molecular Weight | 221.2988 | |
| Molecular Formula | C12H19N3O | |
| CAS Number | 671-16-9 | |
| SMILES | CNNCC1=CC=C(C=C1)C(=O)NC(C)C | |
| External Links | ||
| DRUGBANK | DB01168 | |
| T3DB | T3D4711 | |
| PubChem Compound | 4915 | |
| PDR | 2727 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.06 | - | 0.06 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 223.0 | ℃ | 223 | ℃ | DRUGBANK |
| Water Solubility | 1420.0 | mg/L | 1420 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 100.0 | % | 100 | % | DRUGBANK | |
| Half-life | 0.17 | h | 10 | min | DRUGBANK | |
| Toxicity LD50 | 785.0 | mg/kg | 785.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 785.0 | mg/kg | 785.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 6.0 | mg/kg/day | 6 | mg/kg/day | PO, oral | Matulane | procarbazine hydrochloride | PDR |
| Max dose for children | 100.0 | mg/m2/day | 100 | mg/m2/day | PO, oral | Matulane | procarbazine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1