Basic Information
| Drug ID | DDPD01166 |
|
| Drug Name | Cilostazol | |
| Molecular Weight | 369.4607 | |
| Molecular Formula | C20H27N5O2 | |
| CAS Number | 73963-72-1 | |
| SMILES | O=C1CCC2=C(N1)C=CC(OCCCCC1=NN=NN1C1CCCCC1)=C2 | |
| External Links | ||
| DRUGBANK | DB01166 | |
| PubChem Compound | 2754 | |
| PDR | 2038 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.3 | - | 2.3 | - | DRUGBANK |
| Melting Point | 160.0 | ℃ | 160 | ℃ | PhysProp |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 12.0 | h | 11-13 | h | DRUGBANK | |
| Toxicity LD50 | 5000.0 | mg/kg | >5.0 | g/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 2000.0 | mg/kg | >2.0 | g/kg | PO, oral; dog; | DRUGBANK |
| Eliminate Route | 74.0 | % | 74 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 20.0 | % | 20 | % | Faeces excretion; | DRUGBANK |
| Protein Binding | 96.5 | % | 95-98 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 200.0 | mg/day | 200 | mg/day | PO, oral | Pletal | cilostazol | PDR |
| Max dose for elderly | 200.0 | mg/day | 200 | mg/day | PO, oral | Pletal | cilostazol | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1