Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01161 ...
Drug Name Chloroprocaine
Molecular Weight 270.755
Molecular Formula C13H19ClN2O2
CAS Number 133-16-4
SMILES CCN(CC)CCOC(=O)C1=C(Cl)C=C(N)C=C1
External Links
DRUGBANK DB01161
T3DB T3D3003
PubChem Compound 8612
PDR 2745

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.86 - 2.86 - HANSCH,C ET AL. (1995)
Melting Point 173.5 ℃ 173-174 ℃ Marks, H.C. and Rubin, M.I.; US. Patent 2,460,139; January 25,1949; assigned to Wallace & Tiernan Products, Inc.
Water Solubility 665.0 mg/L 0.665 mg/ml DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Half-life 0.005833 h 21±2 second DRUGBANK
Toxicity LD50 97.0 mg/kg 97.0 mg/kg intravenous injection, IV; mouse; DRUGBANK
Toxicity LD50 950.0 mg/kg 950.0 mg/kg subcutaneous injection, SC; mouse; DRUGBANK
Toxicity LD50 97.0 mg/kg 97.0 mg/kg intravenous injection, IV; mouse; T3DB
Toxicity LD50 950.0 mg/kg 950.0 mg/kg subcutaneous injection, SC; mouse; T3DB

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 11.0 mg/kg 11 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for infants 11.0 mg/kg 11 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for children 11.0 mg/kg 11 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for children 11.0 mg/kg 11 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for adolescents 50.0 mg/dose 50 mg/dose intrathecal administration Nesacaine chloroprocaine hydrochloride PDR
Max dose for adolescents 11.0 mg/kg 11 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for adolescents 800.0 mg/dose 800 mg/dose Nesacaine chloroprocaine hydrochloride PDR
Max dose for adolescents 14.0 mg/kg 14 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for adolescents 1000.0 mg 1000 mg Nesacaine chloroprocaine hydrochloride PDR
Max dose for geriatric 50.0 mg/dose 50 mg/dose Nesacaine chloroprocaine hydrochloride PDR
Max dose for geriatric 11.0 mg/kg 11 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for geriatric 800.0 mg/dose 800 mg/dose Nesacaine chloroprocaine hydrochloride PDR
Max dose for geriatric 14.0 mg/kg 14 mg/kg Nesacaine chloroprocaine hydrochloride PDR
Max dose for geriatric 1000.0 mg 1000 mg Nesacaine chloroprocaine hydrochloride PDR

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1