Basic Information

Drug ID DDPD01158 ...
Drug Name Bretylium
Molecular Weight 243.163
Molecular Formula C11H17BrN
CAS Number 59-41-6
SMILES CC[N+](C)(C)CC1=CC=CC=C1Br
External Links
DRUGBANK DB01158
PubChem Compound 2431

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 238.0 238 Fryer, R.I., Schmidt, R.A. and Sternbach, L.H.; U.S. Patent 3,100,770; August 13, 1963; assigned to Hoffmann-LaRoche Inc. Fryer, R.I., Schmidt, R.A. and Sternbach, L.H.; U.S. Patent 3,182,065; May 4, 1965; assigned to Hoffmann-LaRoche Inc. Fryer, R.I., Schmidt, R.A. and Sternbach, L.H.; US. Patent 3,182,067; May 4, 1965; assigned to Hoffmann-LaRoche Inc.

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Metabolic 0 % 0 % human, homo sapiens; animals; DRUGBANK
Half-life 7.8 h 7.8±0.6(6.9-8.1) h terminal half-life; normal,healthy; DRUGBANK
Half-life 13.0 h 13 h DRUGBANK
Toxicity LD50 400.0 mg/kg 400.0 mg/kg PO, oral; mouse; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1