Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01158 ...
Drug Name Bretylium
Molecular Weight 243.163
Molecular Formula C11H17BrN
CAS Number 59-41-6
SMILES CC[N+](C)(C)CC1=CC=CC=C1Br
External Links
DRUGBANK DB01158
PubChem Compound 2431

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 238.0 ℃ 238 ℃ Fryer, R.I., Schmidt, R.A. and Sternbach, L.H.; U.S. Patent 3,100,770; August 13, 1963; assigned to Hoffmann-LaRoche Inc. Fryer, R.I., Schmidt, R.A. and Sternbach, L.H.; U.S. Patent 3,182,065; May 4, 1965; assigned to Hoffmann-LaRoche Inc. Fryer, R.I., Schmidt, R.A. and Sternbach, L.H.; US. Patent 3,182,067; May 4, 1965; assigned to Hoffmann-LaRoche Inc.

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Metabolic 0 % 0 % human, homo sapiens; animals; DRUGBANK
Half-life 7.8 h 7.8±0.6(6.9-8.1) h terminal half-life; normal,healthy; DRUGBANK
Half-life 13.0 h 13 h DRUGBANK
Toxicity LD50 400.0 mg/kg 400.0 mg/kg PO, oral; mouse; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1