Basic Information
| Drug ID | DDPD01155 |
|
| Drug Name | Gemifloxacin | |
| Molecular Weight | 389.3809 | |
| Molecular Formula | C18H20FN5O4 | |
| CAS Number | 175463-14-6 | |
| SMILES | CO\N=C1/CN(CC1CN)C1=NC2=C(C=C1F)C(=O)C(=CN2C1CC1)C(O)=O | |
| External Links | ||
| DRUGBANK | DB01155 | |
| PubChem Compound | 9571107 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.3 | - | 2.3 | - | DRUGBANK |
| Water Solubility | 350000.0 | mg/L | 350 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 71.0 | % | 71 | % | PO, oral; | DRUGBANK |
| Metabolic | 10.0 | % | 10 | % | Liver metabolism; | DRUGBANK |
| Clearance | 11.6 | L/h | 11.6±3.9 | L/h | Renal clearance; Oral multiple dose; normal,healthy; | DRUGBANK |
| Volume of Distribution | 6.9 | L/kg | 1.66-12.12 | L/kg | DRUGBANK | |
| Half-life | 7.0 | h | 7±2 | h | DRUGBANK | |
| Eliminate Route | 61.0 | % | 61±9.5 | % | Faeces excretion; PO, oral; normal,healthy; human, homo sapiens; | DRUGBANK | Eliminate Route | 36.0 | % | 36±9.3 | % | Urinary excretion; PO, oral; normal,healthy; human, homo sapiens; | DRUGBANK |
| Protein Binding | 65.0 | % | 60-70 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1