Basic Information
| Drug ID | DDPD01150 |
|
| Drug Name | Cefprozil | |
| Molecular Weight | 389.426 | |
| Molecular Formula | C18H19N3O5S | |
| CAS Number | 92665-29-7 | |
| SMILES | [H][C@]12SCC(C=CC)=C(N1C(=O)[C@@]2([H])NC(=O)[C@H](N)C1=CC=C(O)C=C1)C(O)=O | |
| External Links | ||
| DRUGBANK | DB01150 | |
| PubChem Compound | 5281006 | |
| PDR | 1196 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.6 | - | 0.6 | - | DRUGBANK |
| Melting Point | 221.5 | ℃ | 218-225 | ℃ | DRUGBANK |
| Water Solubility | 55.0 | mg/L | 55 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 95.0 | % | 95 | % | DRUGBANK | |
| Clearance | 0.18 | L/h/kg | 3.0 | ml/min/kg | fasting; | DRUGBANK | Clearance | 0.17 | L/h/kg | 2.9 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.23 | L/kg | 0.23 | L/kg | DRUGBANK | Volume of Distribution | 0.21 | L/kg | 0.21 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.3 | h | 1.3 | h | DRUGBANK | Half-life | 1.2 | h | 1.2 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 36.0 | % | 36 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 30.0 | mg/kg/day | 30 | mg/kg/day | PO, oral | Cefprozil | cefprozil | PDR |
| Max dose for children | 30.0 | mg/kg/day | 30 | mg/kg/day | PO, oral | Cefprozil | cefprozil | PDR |
| Max dose for adolescents | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Cefprozil | cefprozil | PDR |
| Max dose for adults | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Cefprozil | cefprozil | PDR |
| Max dose for geriatric | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Cefprozil | cefprozil | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1