Basic Information
| Drug ID | DDPD01140 |
|
| Drug Name | Cefadroxil | |
| Molecular Weight | 363.388 | |
| Molecular Formula | C16H17N3O5S | |
| CAS Number | 50370-12-2 | |
| SMILES | [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=C(O)C=C1)C(O)=O | |
| External Links | ||
| DRUGBANK | DB01140 | |
| PubChem Compound | 47965 | |
| PDR | 1081 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.4 | - | -0.4 | - | DRUGBANK |
| Melting Point | 197.0 | ℃ | 197 | ℃ | lshirnaru.T.and Kodarna.Y.: US. Patent 3864340; February 4,1975; assigned to Toyama Chemical Co. Ltd. (Japan) Crast, L.B. Jr. and Gottstein, W.J.; U S . Patent 3,985,741; October 12,1976; assigned to Bristol-Mvers Co. |
| Water Solubility | 1110.0 | mg/L | 1110 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.15 | L/h/kg | 2.5 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.23 | L/kg | 0.23 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.5 | h | 1.5 | h | DRUGBANK | Half-life | 1.1 | h | 1.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 90.0 | % | >90 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 28.1 | % | 28.1 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 30.0 | mg/kg/day | 30 | mg/kg/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for children | 30.0 | mg/kg/day | 30 | mg/kg/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for children | 2000.0 | mg/day | 2 | g/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for children | 50.0 | mg/kg | 50 | mg/kg | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for children | 2000.0 | mg | 2 | g | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for adolescents | 30.0 | mg/kg/day | 30 | mg/kg/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for adolescents | 2000.0 | mg/day | 2 | g/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for adults | 2000.0 | mg/day | 2 | g/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
| Max dose for elderly | 2000.0 | mg/day | 2 | g/day | PO, oral | Cefadroxil For Oral Suspension | cefadroxil | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1