Basic Information
| Drug ID | DDPD01138 |
|
| Drug Name | Sulfinpyrazone | |
| Molecular Weight | 404.482 | |
| Molecular Formula | C23H20N2O3S | |
| CAS Number | 57-96-5 | |
| SMILES | O=C1C(CCS(=O)C2=CC=CC=C2)C(=O)N(N1C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB01138 | |
| PubChem Compound | 5342 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.3 | - | 2.3 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 136.5 | ℃ | 136-137 | ℃ | PhysProp |
| Water Solubility | 31.2 | mg/L | 31.2 | mg/L | DRUGBANK |
| pKa | 3.25 | - | 3.25 | - | SANGSTER (1994) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0204 | L/h/kg | 0.34 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.12 | L/kg | 0.12 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 5.0 | h | ~4-6 | h | DRUGBANK | Half-life | 6.2 | h | 6.2 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 98.5 | % | 98-99 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1