Basic Information
| Drug ID | DDPD01113 |
|
| Drug Name | Papaverine | |
| Molecular Weight | 339.385 | |
| Molecular Formula | C20H21NO4 | |
| CAS Number | 58-74-2 | |
| SMILES | COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1 | |
| External Links | ||
| DRUGBANK | DB01113 | |
| PubChem Compound | 4680 | |
| PDR | 24173 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.0 | - | 3.0 | - | DRUGBANK |
| Melting Point | 226.0 | ℃ | 226 | ℃ | PhysProp |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.66 | L/h/kg | 11 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 1.0 | L/kg | 1 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.3 | h | 0.5-2 | h | DRUGBANK | Half-life | 1.8 | h | 1.8 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 90.0 | % | ~90 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 600.0 | mg/day | 600 | mg/day | Capsule, PO, Oral | Papaverine Hydrochloride | papaverine hydrochloride | PDR |
| Max dose for geriatric | 600.0 | mg/day | 600 | mg/day | Capsule, PO, Oral | Papaverine Hydrochloride | papaverine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1