| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| AUC |
55200.0 |
ng.h/ml |
55.2±35.1 |
mcg.h/ml |
Tablet, PO, oral; normal,healthy; |
DRUGBANK |
AUC |
477.3 |
ng.h/ml |
477.3 |
ng.h/ml |
Vaginal Administration; |
DRUGBANK |
| C Max |
15100.0 |
ng/ml |
15.1±16.2 |
mcg/ml |
Tablet, PO, oral; normal,healthy; |
DRUGBANK |
C Max |
10.7 |
ng/ml |
10.71 |
ng/ml |
Vaginal Administration; |
DRUGBANK |
| T Max |
7.0 |
h |
7(2-24.1) |
h |
Tablet, PO, oral; normal,healthy; |
DRUGBANK |
T Max |
18.4 |
h |
18.4 |
h |
Vaginal Administration; |
DRUGBANK |
| Clearance |
0.57 |
L/h/kg |
9.48 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
95546.0 |
L |
95546.0 |
L |
Apparent volume of distribution; Vaginal Administration; |
DRUGBANK |
Volume of Distribution |
10911.0 |
L |
10911.0 |
L |
Apparent volume of distribution; Vaginal Administration; |
DRUGBANK |
Volume of Distribution |
7.1 |
L/kg |
7.14 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
24.0 |
h |
24 |
h |
terminal half-life; |
DRUGBANK |
Half-life |
19.8 |
h |
19.75 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 |
3800.0 |
mg/kg |
3800.0 |
mg/kg |
PO, oral; mouse; |
T3DB |
Toxicity LD50 |
3000.0 |
mg/kg |
3.0 |
g/kg |
PO, oral; Rattus, Rat; |
T3DB |
| Eliminate Route |
1.0 |
% |
<1 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
