Basic Information
| Drug ID | DDPD01105 |
|
| Drug Name | Sibutramine | |
| Molecular Weight | 279.848 | |
| Molecular Formula | C17H26ClN | |
| CAS Number | 106650-56-0 | |
| SMILES | CC(C)CC(N(C)C)C1(CCC1)C1=CC=C(Cl)C=C1 | |
| External Links | ||
| DRUGBANK | DB01105 | |
| T3DB | T3D2986 | |
| PubChem Compound | 5210 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 5.2 | - | 5.2 | - | DRUGBANK |
| Melting Point | 191.5 | ℃ | 191-192 | ℃ | DRUGBANK |
| Water Solubility | 2900.0 | mg/L | 2.9 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 77.0 | % | >77 | % | Oral single dose; | DRUGBANK |
| Clearance | 1750.0 | L/h | 1750.0 | L/h | PO, oral; | DRUGBANK |
| Half-life | 1.1 | h | 1.1 | h | DRUGBANK | |
| Eliminate Route | 77.0 | % | 77 | % | Urinary excretion; Oral single dose; | DRUGBANK | Eliminate Route | 8.0 | % | ~8 | % | Faeces excretion; Oral single dose; | DRUGBANK |
| Protein Binding | 97.0 | % | 97 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1