Basic Information
| Drug ID | DDPD01087 |
|
| Drug Name | Primaquine | |
| Molecular Weight | 259.3467 | |
| Molecular Formula | C15H21N3O | |
| CAS Number | 90-34-6 | |
| SMILES | COC1=CC(NC(C)CCCN)=C2N=CC=CC2=C1 | |
| External Links | ||
| DRUGBANK | DB01087 | |
| PubChem Compound | 4908 | |
| PDR | 1912 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.1 | - | 2.1 | - | DRUGBANK |
| Boiling Point | 177.0 | ℃ | 177 | ℃ | PhysProp |
| Melting Point | 25.0 | ℃ | <25 | ℃ | PhysProp |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.35 | L/h/kg | 5.8 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 4.0 | L/kg | 4 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 5.6 | h | 3.7-7.4 | h | DRUGBANK | Half-life | 7.1 | h | 7.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 0.3 | mg/kg/day | 0.3 | mg/kg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
| Max dose for children | 30.0 | mg/day | 30 | mg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
| Max dose for adolescents | 30.0 | mg/day | 30 | mg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
| Max dose for adults | 15.0 | mg/day | 15 | mg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
| Max dose for adults | 30.0 | mg/day | 30 | mg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
| Max dose for elderly | 15.0 | mg/day | 15 | mg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
| Max dose for elderly | 30.0 | mg/day | 30 | mg/day | PO, oral | Primaquine Phosphate | primaquine phosphate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1