Basic Information
| Drug ID | DDPD01085 |
|
| Drug Name | Pilocarpine | |
| Molecular Weight | 208.2569 | |
| Molecular Formula | C11H16N2O2 | |
| CAS Number | 92-13-7 | |
| SMILES | CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O | |
| External Links | ||
| DRUGBANK | DB01085 | |
| T3DB | T3D2979 | |
| PubChem Compound | 5910 | |
| PDR | 2235 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.1 | - | 1.1 | - | DRUGBANK |
| Melting Point | 204.5 | ℃ | 204-205 | ℃ | PhysProp |
| Water Solubility | 1000000.0 | mg/L | 1000000 | mg/L | SEIDELL,A 1941) |
| pKa | 6.78 | - | 6.78 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 0.76 | h | 0.76 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 10.0 | mg/dose | 10 | mg/dose | PO, oral | Salagen | pilocarpine hydrochloride | PDR |
| Max dose for adults | 30.0 | mg/day | 30 | mg/day | PO, oral | Salagen | pilocarpine hydrochloride | PDR |
| Max dose for elderly | 10.0 | mg/dose | 10 | mg/dose | PO, oral | Salagen | pilocarpine hydrochloride | PDR |
| Max dose for elderly | 30.0 | mg/day | 30 | mg/day | PO, oral | Salagen | pilocarpine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1