Basic Information
| Drug ID | DDPD01084 |
|
| Drug Name | Emedastine | |
| Molecular Weight | 302.4145 | |
| Molecular Formula | C17H26N4O | |
| CAS Number | 87233-61-2 | |
| SMILES | CCOCCN1C(=NC2=CC=CC=C12)N1CCCN(C)CC1 | |
| External Links | ||
| DRUGBANK | DB01084 | |
| PubChem Compound | 3219 | |
| PDR | 1093 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.6 | - | 2.6 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 3.5 | h | 3-4 | h | elimination half-life; PO, oral; | DRUGBANK |
| Eliminate Route | 44.0 | % | ~44 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 3.6 | % | 3.6 | % | Urinary excretion; PO, oral; Unchanged drug; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 4.0 | drop/day | 4 | drop/day | ophthalmic administration | Emadine | emedastine difumarate | PDR |
| Max dose for adolescents | 4.0 | drop/day | 4 | drop/day | ophthalmic administration | Emadine | emedastine difumarate | PDR |
| Max dose for adults | 4.0 | drop/day | 4 | drop/day | ophthalmic administration; ophthalmic solution | Emadine | emedastine difumarate | PDR |
| Max dose for elderly | 4.0 | drop/day | 4 | drop/day | ophthalmic administration | Emadine | emedastine difumarate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1