Basic Information
| Drug ID | DDPD01083 |
|
| Drug Name | Orlistat | |
| Molecular Weight | 495.7348 | |
| Molecular Formula | C29H53NO5 | |
| CAS Number | 96829-58-2 | |
| SMILES | CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O | |
| External Links | ||
| DRUGBANK | DB01083 | |
| PubChem Compound | 3034010 | |
| PDR | 2101 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 8.6 | - | 8.6 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 1.5 | h | 1-2 | h | DRUGBANK | |
| Protein Binding | 99.0 | % | >99 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 360.0 | mg/day | 360 | mg/day | PO, oral | Xenical | orlistat | PDR |
| Max dose for adolescents | 360.0 | mg/day | 360 | mg/day | PO, oral | Xenical | orlistat | PDR |
| Max dose for adults | 360.0 | mg/day | 360 | mg/day | PO, oral | Xenical | orlistat | PDR |
| Max dose for adults | 180.0 | mg/day | 180 | mg/day | PO, oral | Xenical | orlistat | PDR |
| Max dose for geriatric | 360.0 | mg/day | 360 | mg/day | PO, oral | Xenical | orlistat | PDR |
| Max dose for geriatric | 180.0 | mg/day | 180 | mg/day | PO, oral | Xenical | orlistat | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1