Basic Information
| Drug ID | DDPD01082 |
|
| Drug Name | Streptomycin | |
| Molecular Weight | 581.5741 | |
| Molecular Formula | C21H39N7O12 | |
| CAS Number | 57-92-1 | |
| SMILES | CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]2NC(N)=N)O[C@@H](C)[C@]1(O)C=O | |
| External Links | ||
| DRUGBANK | DB01082 | |
| PubChem Compound | 19649 | |
| PDR | 1600 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -6.4 | - | -6.4 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.5 | h | 1-2 | h | IM,intramuscular injection; | DRUGBANK |
| Clearance | 0.0468 | L/h/kg | 0.78 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.34 | L/kg | 0.34 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 5.5 | h | 5-6 | h | adults; normal renal function; | DRUGBANK | Half-life | 4.3 | h | 4.3 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 430.0 | mg/kg | 430.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 40.0 | mg/kg/day | 40 | mg/kg/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
| Max dose for children | 40.0 | mg/kg/day | 40 | mg/kg/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
| Max dose for children | 2000.0 | mg/day | 2 | g/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
| Max dose for adolescents | 40.0 | mg/kg/day | 40 | mg/kg/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
| Max dose for adolescents | 2000.0 | mg/day | 2 | g/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
| Max dose for adults | 2000.0 | mg/day | 2 | g/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
| Max dose for geriatric | 2000.0 | mg/day | 2 | g/day | intravenous injection, IV;IM,intramuscular injection; | Streptomycin | streptomycin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1