Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01081 ...
Drug Name Diphenoxylate
Molecular Weight 452.5873
Molecular Formula C30H32N2O2
CAS Number 915-30-0
SMILES CCOC(=O)C1(CCN(CCC(C#N)(C2=CC=CC=C2)C2=CC=CC=C2)CC1)C1=CC=CC=C1
External Links
DRUGBANK DB01081
T3DB T3D2978
PubChem Compound 13505

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 6.3 - 6.3 - DRUGBANK
Melting Point 221.25 ℃ 220.5-222 ℃ Janssen, P.A.J.; U.S.Patent 2,898,340; August 4,1959. Dryden, H.L. Jr. and Erickson, R.A.; U.S. Patent 4,086,234; April 25,1978; assigned to G.D.Searle & Co.
Water Solubility 800.0 mg/L 800 mg/L MERCK INDEX 1996)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 90.0 % 90 % DRUGBANK
Half-life 13.0 h 12-14 h DRUGBANK
Protein Binding 84.5 % 74-95 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1