Basic Information
| Drug ID | DDPD01066 |
|
| Drug Name | Cefditoren | |
| Molecular Weight | 506.578 | |
| Molecular Formula | C19H18N6O5S3 | |
| CAS Number | 104145-95-1 | |
| SMILES | [H][C@]12SCC(\C=C/C3=C(C)N=CS3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CSC(N)=N1)C(O)=O | |
| External Links | ||
| DRUGBANK | DB01066 | |
| PubChem Compound | 9870843 | |
| PDR | 831 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 128.0 | ℃ | 127-129 | ℃ | DRUGBANK |
| Water Solubility | 100.0 | mg/L | <0.1 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 14.0 | % | 14 | % | PO, oral; fasting; Active metabolite; | DRUGBANK | Bioavailability | 16.0 | % | 16±3 | % | PO, oral; low fat meal; Active metabolite; | DRUGBANK |
| Clearance | 4.5 | L/h | 4.0-5 | L/h | Renal clearance; PO, oral; | DRUGBANK |
| Volume of Distribution | 9.3 | L | 9.3±1.6 | L | DRUGBANK | |
| Half-life | 1.6 | h | 1.6±0.4 | h | elimination half-life; young; normal,healthy; adults; | DRUGBANK |
| Eliminate Route | 99.0 | % | >99 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 88.0 | % | 88 | % | plasma proteins; high protein binding; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 800.0 | mg/day | 800 | mg/day | PO, oral | Spectracef | cefditoren pivoxil | PDR |
| Max dose for adolescents | 800.0 | mg/day | 800 | mg/day | PO, oral | Spectracef | cefditoren pivoxil | PDR |
| Max dose for adults | 800.0 | mg/day | 800 | mg/day | PO, oral | Spectracef | cefditoren pivoxil | PDR |
| Max dose for elderly | 800.0 | mg/day | 800 | mg/day | PO, oral | Spectracef | cefditoren pivoxil | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1