Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01061 ...
Drug Name Azlocillin
Molecular Weight 461.492
Molecular Formula C20H23N5O6S
CAS Number 37091-66-0
SMILES [H][C@](NC(=O)N1CCNC1=O)(C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@]12[H])C1=CC=CC=C1
External Links
DRUGBANK DB01061
PubChem Compound 6479523

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 0.2 - 0.2 - DRUGBANK
Water Solubility 50000.0 mg/L 50 mg/ml DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.15 L/h/kg 2.5 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.26 L/kg 0.26 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.4 h 1.3-1.5 h elimination half-life; DRUGBANK
Half-life 4.0 h 2-6 h RD, renal impairment, Renal disease，including uremia; patients; DRUGBANK
Half-life 1.2 h 1.2 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 33.0 % 20-46 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1