Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
Bioavailability |
100.0 |
% |
~100 |
% |
PO, oral; food; |
food → ; |
DRUGBANK |
Clearance |
0.13 |
L/h/kg |
2.2 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
1.8 |
L/kg |
1.8 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
Half-life |
15.0 |
h |
~15 |
h |
elimination half-life; patients; |
|
DRUGBANK |
Half-life |
35.0 |
h |
35 |
h |
severe renal function; |
|
DRUGBANK |
Half-life |
12.0 |
h |
12 |
h |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
Toxicity LD50 |
800.0 |
mg/kg |
~800 |
mg/kg |
PO, oral; mouse; |
|
DRUGBANK |
Toxicity LD50 |
1000.0 |
mg/kg |
1000.0 |
mg/kg |
PO, oral; Rattus, Rat; |
|
DRUGBANK |
Toxicity LD50 |
230.0 |
mg/kg |
230.0 |
mg/kg |
PO, oral; guinea pigs; |
|
DRUGBANK |