Basic Information
| Drug ID | DDPD00990 |
|
| Drug Name | Exemestane | |
| Molecular Weight | 296.4034 | |
| Molecular Formula | C20H24O2 | |
| CAS Number | 107868-30-4 | |
| SMILES | [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC(=C)C2=CC(=O)C=C[C@]12C | |
| External Links | ||
| DRUGBANK | DB00990 | |
| PubChem Compound | 60198 | |
| PDR | 475 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.7 | - | 3.7 | - | DRUGBANK |
| Melting Point | 155.13 | ℃ | 155.13 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 42.0 | % | 42 | % | DRUGBANK | |
| Half-life | 24.0 | h | 24 | h | DRUGBANK | |
| Protein Binding | 90.0 | % | 90 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 25.0 | mg/day | 25 | mg/day | PO, oral | Aromasin | exemestane | PDR |
| Max dose for adults | 50.0 | mg/day | 50 | mg/day | PO, oral | Aromasin | exemestane | PDR |
| Max dose for elderly | 25.0 | mg/day | 25 | mg/day | PO, oral | Aromasin | exemestane | PDR |
| Max dose for elderly | 50.0 | mg/day | 50 | mg/day | PO, oral | Aromasin | exemestane | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1