| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Absorption |
20.0 |
% |
<20 |
% |
PO, oral; |
DRUGBANK |
| Bioavailability |
20.0 |
% |
<20 |
% |
PO, oral; |
The Pharmacological Basis of Therapeutics |
| C Max |
5000.0 |
ng/ml |
~5 |
mcg/ml |
intravenous injection, IV; leukemia; malignant solid tumors; |
The Pharmacological Basis of Therapeutics |
C Max |
75.0 |
ng/ml |
0.05-0.1 |
mcg/ml |
intravenous infusion, IV in drop; leukemia; malignant solid tumors; |
The Pharmacological Basis of Therapeutics |
| Clearance |
0.78 |
L/h/kg |
13±4 |
ml/min/kg |
|
The Pharmacological Basis of Therapeutics |
Clearance |
2.5 |
L/h/kg |
41.67 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
3.0 |
L/kg |
3.0±11.9 |
L/kg |
|
The Pharmacological Basis of Therapeutics |
Volume of Distribution |
0.67 |
L/kg |
0.67 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
0.17 |
h |
10 |
min |
|
DRUGBANK |
Half-life |
2.6 |
h |
2.6±0.6 |
h |
|
The Pharmacological Basis of Therapeutics |
Half-life |
0.17 |
h |
0.17 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
11.0 |
% |
11±8 |
% |
Urinary excretion; Unchanged drug; |
The Pharmacological Basis of Therapeutics |
| Protein Binding |
13.0 |
% |
13 |
% |
|
DRUGBANK |
Protein Binding |
13.0 |
% |
13 |
% |
|
The Pharmacological Basis of Therapeutics |
