Basic Information
| Drug ID | DDPD00986 |
|
| Drug Name | Glycopyrronium | |
| Molecular Weight | 318.4305 | |
| Molecular Formula | C19H28NO3 | |
| CAS Number | 740028-90-4 | |
| SMILES | C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00986 | |
| PubChem Compound | 9933193 | |
| PDR | 1135 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.99 | - | -0.99 | - | DRUGBANK |
| Melting Point | 193.75 | ℃ | 193-194.5 | ℃ | U.S. Patent 2,956,062. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 0.90 | h | 0.6-1.2 | h | DRUGBANK | |
| Toxicity LD50 | 709.0 | mg/kg | 709.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 6.0 | mg/day | 6 | mg/day | Tablet,PO，oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for children | 0.3 | mg/kg/day | 0.1 | mg/kg/dose | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for children | 3.0 | mg/dose | 3 | mg/dose | Liquid | Robinul Injection | glycopyrrolate | PDR |
| Max dose for children | 0.3 | mg/kg/day | 0.1 | mg/kg/dose | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for children | 3.0 | mg/day | 3 | mg/day | Liquid | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adolescents | 6.0 | mg/day | 6 | mg/day | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adolescents | 0.1 | mg/kg/dose | 0.1 | mg/kg/dose | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adolescents | 3.0 | mg/dose | 3 | mg/dose | Liquid | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adolescents | 0.1 | mg/kg/dose | 0.1 | mg/kg/dose | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adolescents | 3.0 | mg/day | 3 | mg/day | Liquid | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 0.004 | mg/kg | 0.004 | mg/kg | IM,intramuscular injection | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 0.2 | mg/dose | 0.2 | mg/dose | intravenous injection, IV | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 6.0 | mg/day | 6 | mg/day | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 2.0 | capsuLe/day | 2 | capsuLe/day | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 0.0312 | mg | 31.2 | mcg | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 2.0 | viaLs/day | 2 | viaLs/day | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for adults | 0.05 | mg | 50 | mcg | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 0.004 | mg/kg | 0.004 | mg/kg | IM,intramuscular injection | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 0.2 | mg/dose | 0.2 | mg/dose | intravenous injection, IV | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 6.0 | mg/day | 6 | mg/day | PO, oral | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 2.0 | capsule/day | 2 | capsule/day | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 0.0312 | mg | 31.2 | mcg | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 2.0 | vials/day | 2 | vials/day | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
| Max dose for geriatric | 0.05 | mg | 50 | mcg | inhalation, IH | Robinul Injection | glycopyrrolate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1