Basic Information
| Drug ID | DDPD00981 |
|
| Drug Name | Physostigmine | |
| Molecular Weight | 275.3461 | |
| Molecular Formula | C15H21N3O2 | |
| CAS Number | 57-47-6 | |
| SMILES | [H][C@]12N(C)CC[C@@]1(C)C1=C(C=CC(OC(=O)NC)=C1)N2C | |
| External Links | ||
| DRUGBANK | DB00981 | |
| PubChem Compound | 5983 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.58 | - | 1.58 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 105.5 | ℃ | 105.5 | ℃ | PhysProp |
| Water Solubility | 7760.0 | mg/L | 7760 | mg/L | DRUGBANK |
| pKa | 6.12 | - | 6.12 | - | MERCK INDEX (1996) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 4.3 | L/h/kg | 72 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 3.9 | L/kg | 3.9 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.0 | h | 1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1