Basic Information

Drug ID DDPD00980 ...
Drug Name Ramelteon
Molecular Weight 259.3434
Molecular Formula C16H21NO2
CAS Number 196597-26-9
SMILES CCC(=O)NCC[C@@H]1CCC2=C1C1=C(OCC1)C=C2
External Links
DRUGBANK DB00980
PubChem Compound 208902
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.4 - 2.4 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 84.0 % >84 % DRUGBANK
Clearance 0.79 L/h/kg 13.1 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 73.6 L 73.6 L DRUGBANK
Volume of Distribution 1.1 L/kg 1.05 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.8 h ~1-2.6 h DRUGBANK
Half-life 1.9 h 1.9 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 84.0 % 84 % Urinary excretion; PO, oral; DRUGBANK
Eliminate Route 4.0 % ~4 % Faeces excretion; PO, oral; DRUGBANK
Protein Binding 82.0 % ~82 % human, homo sapiens; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1