Basic Information

Drug ID DDPD00969 ...
Drug Name Alosetron
Molecular Weight 294.351
Molecular Formula C17H18N4O
CAS Number 122852-42-0
SMILES CN1C2=C(C3=CC=CC=C13)C(=O)N(CC1=C(C)NC=N1)CC2
External Links
DRUGBANK DB00969
PubChem Compound 2099
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.0 - 2.0 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 55.0 % 50-60 % DRUGBANK
Clearance 36.0 L/h 600.0 ml/min DRUGBANK
Clearance 0.52 L/h/kg 8.7 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 80.0 L 65-95 L DRUGBANK
Volume of Distribution 1.1 L/kg 1.1 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.5 h 1.5 h DRUGBANK
Half-life 1.6 h 1.6 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 6.0 % ~6 % Urinary excretion; Unchanged drug; DRUGBANK
Protein Binding 82.0 % 82 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1